Grants and Contributions
About this information
In June 2016, as part of the Open Government Action Plan, the Treasury Board of Canada Secretariat (TBS) committed to increasing the transparency and usefulness of grants and contribution data and subsequently launched the Guidelines on the Reporting of Grants and Contributions Awards, effective April 1, 2018.
The rules and principles governing government grants and contributions are outlined in the Treasury Board Policy on Transfer Payments. Transfer payments are transfers of money, goods, services or assets made from an appropriation to individuals, organizations or other levels of government, without the federal government directly receiving goods or services in return, but which may require the recipient to provide a report or other information subsequent to receiving payment. These expenditures are reported in the Public Accounts of Canada. The major types of transfer payments are grants, contributions and \'other transfer payments\'.
Included in this category, but not to be reported under proactive disclosure of awards, are (1) transfers to other levels of government such as Equalization payments as well as Canada Health and Social Transfer payments. (2) Grants and contributions reallocated or otherwise redistributed by the recipient to third parties; and (3) information that would normally be withheld under the Access to Information Act and the Privacy Act.
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$11,641.21
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$15,000.00
Oct 2, 2024
For-profit organization
Develop digital adoption plan
$386,210.00
Oct 2, 2024
Academia
In situ protein manufacturing: systemic LNP-RNA to deliver therapeutic proteins to the brain.
1019162
Neurological disorders affect up to 10% of Canadians, and few treatment options exist. Current understanding of disease pathogenesis suggests that protein replacement or supplementation is an attractive therapeutic approach. However, the development of protein biologics for the brain is marred by two key problems: spatial distribution across the BBB and short protein half-lives. The project will investigate the delivery of protein biologics to the brain using an in situ ‘Bioreactor’ approach. Using lipid nanoparticles encapsulating messenger RNA (LNP-mRNA), a subset of brain cells are instructed to produce and secrete therapeutic proteins continually over the lifespan of stably-modified RNA. Using LNPs that cross the BBB, this unique bioreactor approach could deliver proteins with brain-wide diffusion. This approach only requires limited cell transfection rate, has low cell-specific tropism requirements, and can be adapted to produce proteins for different indications. It therefore represents a platform-enabling translatable strategy for novel nanomedicines for a range of neurological diseases.
$2,652,124.30
Oct 2, 2024
Not-for-profit organization or charity
Strengthening Border Management and Security Practices Points of Entry into Aqaba Governorate
7429459 P010111001
Strengthening Border Management and Security Practices Points of Entry into Aqaba Governorate