Grants and Contributions

Expansion of the Montréal manufacturing capacity for COVID-19 vaccines, diverse injectable drugs and therapeutics with innovative state-of-the-art technology, facility expansion and retrofit and equip

Development and implementation of CANImmunize ClinicFlow to support the COVID-19 vaccine rollout in Canada.

The purpose of this funding opportunity is to support readiness preparations for CIRN to undertake urgent activities related to COVID-19 vaccine clinical trials and to provide vaccine-related research outcomes that will inform effective, equitable and timely COVID-19 public health decision-making. The proposal will address ALL of the following objectives:
• Act with a sense of urgency and coordinate with all relevant stakeholders, including federal, provincial and territorial partners, to ensure Canadian readiness for COVID-19 vaccine clinical trials. Meeting this objective will help to ensure sufficient COVID-19 vaccine clinical trial capacity and infrastructure are in place when needed and will support the accelerated evaluation of COVID-19 vaccine(s) in Canada.
• Proactively communicate with all relevant national and international stakeholders to ensure CIRN is aware of, and aligned with (wherever possible), global COVID-19 vaccine clinical trial strategies to provide the highest possible level of evidence on the safety and efficacy of COVID-19 vaccine(s).
• Assess various models of population prioritization and perform modelling to support the development of evidence-based recommendations for effective and equitable program design and implementation, and knowledge mobilization to mitigate the COVID-19 pandemic.
• Prepare the general public, high-risk populations and the public health community for deployment of COVID-19 vaccine(s), which includes coordinating and/or conducting research related to vaccine hesitancy, acceptance and uptake, and the identification of targeted and culturally appropriate communication and roll-out strategies to optimize uptake.
• Seek opportunities for harmonized data collection, open data sharing, and real-world data sharing with relevant knowledge-users to support a timely and effective COVID-19 public health response within and across all jurisdictions in Canada.

The purpose of this funding opportunity is to better understand the laws and regulations for vaccination that exist across Canada in order to determine whether they support or impede the achievement of vaccination program goals and objectives in both routine and emergency contexts, including the current COVID-19 pandemic. In addition, the study will examine the specific issues of mandatory vaccination and compensation for serious events following vaccination, which are of particular relevance for potential COVID-19 vaccine(s).

The proposal will address all of the following objectives:
•Survey at least 7 Canadian provincial and territorial jurisdictions and create a national map of governance frameworks (e.g., key actors, policies, laws, regulations) and any planned or potential changes resulting from COVID-19 vaccination planning.
•Assess provincial and territorial frameworks to facilitate insights into: (a) the commonalities and discrepancies between frameworks; (b) the extent to which, and how, the frameworks address mandates, compensation, and emergency situations; and (c) whether these frameworks encourage health care worker and public trust in vaccination programs and vaccines.
•Undertake the following in relation to the specific issues of mandatory vaccination and compensation for serious adverse events following vaccination, both of which will be essential as potential COVID-19 vaccine(s) are rolled out: (a) a preliminary examination and comparison of how select Canadian frameworks approach these two critical issues; and (b) a preliminary case study of how select Canadian approaches contrast with relevant select foreign jurisdictions.
•Propose areas for consideration for revisions to regulation of vaccination in Canada, including routine and responsive vaccination goals.

This proposal from the Canadian Red Cross (CRC) follows a request for federal assistance received from the Government of Nova Scotia submitted on December 29, 2021, for support to Nova Scotia’s COVID-19 Immunization Program. The CRC will provide up to 14 immunizers and 10 generalists to support the vaccination effort. 

This project will support the development of Canada’s medical countermeasures (MCMs) in immediate response to COVID-19. Variation Biotechnologies Inc. (VBI) will advance the development of an enveloped Virus-Like-Particle (eVLP) vaccine candidate through clinical trials to provide protection against SARS-COV2 (COVID-19), MERS and SARS.

The project will involve the development of a diagnostic test to detect anti-SARS-CoV-2-specific T cells in a small sample of peripheral blood with initial aim to test vaccine effectiveness in terms of cell mediated immunity and understand which vaccine recipients are potentially immune to COVID-19 to triage vaccine prioritization in Canada.

Following a request for federal assistance from the Province of Saskatchewan, the Canadian Red Cross will support the Federal Government's response by providing surge Health Human Resources to the Saskatchewan Health Authority (SHA).

This Project aims to reduce the incidence of COVID-19 related death and serious illness, particularly amongst priority groups and vulnerable populations, by increasing equitable access to and uptake of COVID-19 vaccines in five countries in the African region. The Project will support health systems strengthening to enable the delivery of gender-equitable COVID-19 vaccination and routine health services.

This Project proposes a modeling platform to quickly explore vaccine designs using simulation and Machine Learning algorithms.