Grants and Contributions

The purpose of this project is to provide funding to support market development activities to expand export opportunities for the Canadian wood products industry.

The type 1 cannabinoid receptor (CB1R) is the receptor that is activated by .9-tetrahydrocannabinol (THC), the chemical in Cannabis
that produces the 'high' Cannabis users experience. THC, and the related cannabidiol (CBD) are known as a cannabinoids and at least
120 other cannabinoids have been identified in the Cannabis plant. Cannabinoids are being explored for their potential use to treat
epilepsy, pain, anxiety, and numerous other ailments. Unfortunately, our knowledge of how cannabinoids work at CB1R is limited. In
this project, we will use computer-assisted drug design programs and drug discovery experiments to understand how cannabinoids
from the Cannabis plant work at the molecular level. Mutant forms of the receptor will be used to help us understand which parts of
CB1R are required for cannabinoids to produce cellular effects. From this study we will gain critical knowledge about how cannabinoids
work with CB1R. This knowledge will lead to improved understanding of cannabinoid biology, safe and effective use of cannabinoids,
and the potential for new cannabinoid drugs.

This project will deliver a practical solution to advance SSB development and contribute to the transition to cleaner transportation in Canada and worldwide.

To accelerate the development of novel biocontrol inoculants against Aphanomyces euteiches (A. euteiches) root rot, the Project expand the suite of bacterial mutagenesis tools that can be used to study the phenomenon’s key underlying mechanisms. New INSeq vectors will be designed and an RBTnSeq protocol will be adapted and optimized. These tools will be applied to understand the basis of efficient A. euteiches antagonism and rhizosphere competitive survival in an array of novel bacterial isolates covering a range of taxonomic affiliations. Mutant pools of each strain will be screened in growth chamber experiments in which pea seedlings are exposed to the biocontrol strain mutants, naturally-occurring microbiomes from Canadian Prairie pea production soils, and/or A. euteiches. These experiments will yield essential bacterial A. euteiches-biocontrol genes, and thus interpret how taxonomically diverse bacteria successfully suppress the pathogen. The latter information will facilitate the selection of strains that show the most promise for field applications.

All-weather optical satellite communications (satellite-to-ground and ground-to-satellite) remain a challenge due to many factors. The Project will develop detectors and receivers suitable for next generation optical satellite communications. During detector development, the size, weight, power, and sensitivity of detectors will be optimized for coherent detection and wavelength division multiplexing (WDM). Examples include multi-channel single-photon avalanche diodes (SPADs), multispectral nanowire infrared (IR) detectors, high sensitivity mid-IR detectors, and Kramers-Kronig coherent receivers.

The purpose of the contribution is to provide funding to create targeted tools to help decrease online hatred and harmful content through the creation of new resources that provide counter speech as the narrative.

P002886

P002888

P002858

P002885