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Evidence of Good Manufacturing Practices (GMP) for drug submissions. The goal of this revision is to better align the drug …

Record Modified: Jul 8, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: drug submission submission filing requirements good manufacturing practices GMP drug establishment licences

This guidance document is specific to the "tamper-resistance" feature of controlled-release opioid products. It is intended for the pre-market review …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document tamper-resistance formulations tamper-resistant properties opioid drug products controlled-release opioid drug formulations controlled-release opioid products drug submissions product monographs

This guidance document applies to sponsors intending to make changes to new drugs that have received a NOC pursuant to …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Post-notice of compliance NOC changes safety and efficacy document changes to new drugs section C.08.004 of the Food and Drug Regulations pharmaceuticals biologics radiopharmaceuticals human use pharmaceutical and certain biotechnological products for veterinary use

After a new drug as defined in section C.08.001 of the Food and Drug Regulations has been granted a Notice …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Post-Notice of Compliance NOC Changes framework document changes to the drug section C.08.004 of the Food and Drug Regulations

This guidance document applies to sponsors intending to make changes to new drugs that have received a NOC pursuant to …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document post-notice of compliance NOC Changes changes to new drugs safety and efficacy document pharmaceutical biologic radiopharmaceutical drugs for human use section C.08.004 of the Food and Drug Regulations

A post-NOC change is any change that is made to a new drug that has received a NOC pursuant to …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Post-Notice of Compliance NOC Changes framework document pharmaceutical biologic radiopharmaceutical drugs drugs for human use only

This guidance document applies to sponsors intending to make changes to new drugs that have received a NOC pursuant to …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Post-Notice of Compliance NOC Changes quality guidance changes to new drugs section C.08.004 of the Food and Drug Regulations pharmaceuticals biologics radiopharmaceuticals drugs for human use biotechnological drugs for veterinary use

Health Canada is publishing this document to be transparent about the principles and factors that it considers when deciding whether …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document determining prescription status for human drugs determining prescription status for veterinary drugs authorized as a prescription or nonprescription product

This guidance aims to articulate Health Canada's expectations and generate a level of consistency regarding the interpretation of the Priority …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance for industry priority review of drug submissions interpretation of the priority review of drug submissions policy priority review request

The purpose of this guidance document is to assist sponsors in developing product monographs with acceptable format and content. Health …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document product monograph product monograph 2020 an integral part of a new drug submission necessary information for the safe and effective use of a new drug