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The Periodic Benefit-Risk Evaluation Report (PBRER) described in this Guideline is intended to be a common standard for periodic benefit-risk …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document periodic benefit-risk evaluation report PBRER International Conference on Harmonisation ICH Topic E2C(R2) reporting on marketed products

Section C.01.018 of Division 1 of the Food and Drug Regulations requires the Market Authorization Holder (MAH) to analyze adverse …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Notice adoption of the International Conference on Harmonisation ICH guidance on Periodic Benefit Risk Evaluation Report ICH Topic E2C(R2) market authorization holder adverse drug reaction data adverse drug reaction annual summary report

The Health Product Vigilance Framework is being developed to strengthen and modernize health product vigilance (PV) practices in Canada. Aligned …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Health product vigilance PV health product vigilance framework health product vigilance practices vigilance framework that manages risks consistently across product lines industry's vigilance responsibilities

To provide market authorization holders direction on the process to be followed and information to be submitted to Health Canada …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document for industry review of drug brand names market authorization a proposed name to be misleading confused with another product authorized for use preventing medication errors

The purpose of this Notice is to notify stakeholders that Health Canada has made changes to the opioid patient information …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Notice to stakeholders opioid patient information handout “Opioid Medicines – Information for Patients and Families” Food and Drug Regulations a warning sticker prescription opioids list of Opioids”.

Health Canada has identified the need for patients to receive clear information about the safe use of opioids and the …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: opioid warning Sticker patient information handout risk management plans receive clear information about the safe use of opioids Food and Drug Regulations prescription opioids “List of Opioids”

This guidance is intended to harmonize and to update the prescribing information for nonsteroidal anti-inflammatory drugs () indicated for controlling …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Basic product mMonograph information non-steroidal anti-inflammatory drugs NSAIDs controlling pain and inflammation rheumatic diseases product monograph contains objective adequate and concise information on drug product safe and effective use of the drug

This document provides information for industry on how Health Canada's Health Products and Food Branch interprets and applies the 2014 …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: questions and answers plain language labelling regulations prescription drugs labelling packaging and brand names of drugs drugs for human use prescription pharmaceutical drugs biologic drugs schedule-D radiopharmaceuticals schedule-C

This document provides information for industry on how Health Canada's Health Products and Food Branch interprets and applies the 2014 …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document plain language labelling regulations non-prescription drugs 2014 Regulations Amending the Food and Drug Regulations labelling packaging and brand names drugs for human use for non-prescription

The Guidance Document: Management of Drug Submissions and Applications (MDSG) gives sponsors and Health Canada staff operational direction and guidance …

Record Modified: Jul 7, 2021
Record Released: Jul 7, 2021
Publisher: Health Canada
Formats: HTML
Keywords: Guidance document management of drug submissions and applications sponsors operational direction managing information submitted during drug submissions and applications