Open Government Portal

Found 10 records similar to Assessing the toxicity of perfluorooctanoic acid (PFOA) to Hyalella azteca and Fathead minnow

Federal

Dataset contains laboratory-studied Fathead minnow (Pimephales promelas) survival when exposed to bitumen sediments from the oil sands region of northern Alberta, cut through the McMurray Formation (MF). These are the results of the toxicological exposures, when Fathead minnow embryos were exposed to water from simulated rainfall on the river sediments.

Last Updated: Jul. 28, 2021
Date Published: May 2, 2019
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  oil sands, fish toxicology, Fathead minnow (Pimephales promelas), contaminants, survival, sediment, Oil Sands Region, Alberta, Athabasca River
Federal

Fathead minnow (Pimephales promelas) embryos and larvae are frequently used in toxicology, including short-term embryo-only tests which often use small volumes of test solution. The effect that such conditions may have on Fathead minnow development has yet to be explicitly described. Here we compared rates of embryonic development in Fathead minnow embryos reared under standard light and temperature conditions with a range of possible methods. All methods yielded excellent control survival.

Last Updated: Feb. 21, 2022
Date Published: Sep. 10, 2018
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  fish embryo toxicity tests, embryo, bioassay, tissue culture plate, embryo movement, methodology development, fish development, Chemicals Management Plan (CMP), Contaminants
Federal

The toxicity of pharmaceuticals finasteride (FIN) and melengestrol acetate (MGA) was assessed in chronic (42 days) sediment tests with the amphipod Hyalella azteca. Two tests were completed for each compound. Survival, growth, reproduction and sex ratio were assessed at the end of each test.

Last Updated: Jan. 24, 2022
Date Published: Feb. 25, 2021
Organization: Environment and Climate Change Canada
Formats: HTML
Keywords:  Aquatic animals, Arthropods, Bioassay, Toxicology, Biology, Chemicals, Fresh water, Sediment, Toxicity
Federal

The toxicity of pharmaceuticals finasteride (FIN) and melengestrol acetate (MGA) was assessed in chronic (42 days) sediment tests with the amphipod Hyalella azteca. Two tests were completed for each compound. Survival, growth, reproduction and sex ratio were assessed at the end of each test.

Last Updated: Jan. 24, 2022
Date Published: Nov. 25, 2021
Organization: Environment and Climate Change Canada
Formats: HTML
Keywords:  amphipod, Hyalella azteca, sediments, toxicity, pharmaceuticals, finasteride, Melengestrol acetate, The New Substances Assessment and Control Bureau (NSACB), Environment
Federal

Venlafaxine is an antidepressant and anti-anxiety drug that has been detected in municipal wastewater at low concentrations. To assess the potential of this compound to affect the survival, development and reproductive capacity of fish, we exposed Fathead minnow (Pimephales promelas) over a full lifecycle in a flow-through system to nominal venlafaxine concentrations. During the 167–168 day exposure, no significant changes were observed in survival, or the weights and lengths of Fathead minnows. At maturity, there were no significant differences relative to controls in condition factor, liver-somatic index, or secondary sex characteristics in the venlafaxine exposed male or female fish.

Last Updated: Jul. 23, 2021
Date Published: May 4, 2018
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  Venlafaxine, Pharmaceutical chemicals, Fathead minnow (Pimephales promelas), life cycle, antidepressant, Chemicals Management Plan (CMP), Contaminants, Biochemicals
Federal

To assess the toxicity of winter-time atmospheric deposition in the oil sands mining area of Northern Alberta, embryo-larval fathead minnow (Pimephales promelas) were exposed to snowmelt samples. Snow was collected in 2011–2014 near (< 7 km) oil sands open pit mining operations in the Athabasca River watershed and at sites far from (> 25 km) oil sands mining. Snow was shipped frozen back to the laboratory, melted, and amended with essential ions prior to testing. Fertilized fathead minnow eggs were exposed (< 24 h post-fertilization to 7–16 days post-hatch) to a range of 25%–100% snowmelt.

Last Updated: Feb. 21, 2019
Date Published: Dec. 28, 2017
Organization: Environment and Climate Change Canada
Formats: HTML JPG
Keywords:  Oil Sands, Snow Meltwater, Fathead minnow, Alberta Oil Sands, Water quality, Environment, Inland waters
Federal

This guideline technical document reviews and assesses all identified health risks associated with PFOA in drinking water. It incorporates available studies and approaches and takes into consideration the availability of appropriate treatment technology. Based on this review, the drinking water guideline for PFOA is a maximum acceptable concentration (MAC) of 0.0002 mg/L (0.2 µg/L), based on the general population.

Last Updated: Sep. 27, 2022
Date Published: Dec. 7, 2018
Organization: Health Canada
Formats: HTML
Keywords:  water, water quality, drinking water quality, potable water, contaminants, exposure to contaminants, Perfluorooctanoic Acid, PFOA, PFOA in drinking-water
Federal

Propranolol is a human pharmaceutical b-blocker that has been detected in municipal wastewater effluents in low concentrations. To assess the potential of this compound to affect fish, Fathead minnow (Pimephales promelas) were exposed for a life cycle in a flow-through system to nominal propranolol concentrations. During the 162-day to 165-day exposure, no significant changes in weights or lengths were seen in Fathead minnows, although the highest concentration of propranolol did cause a 15% decrease in survival of larval and juvenile stage fish compared with controls. At maturity, there were no significant changes in condition factor, liver-somatic index, or secondary sex characteristics in propranolol-exposed male or female fish.

Last Updated: Feb. 21, 2022
Date Published: May 4, 2018
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  Propranolol, Fathead minnow (Pimephales promelas), Life cycle, Pharmaceutical chemicals, toxicity, Chemicals Management Plan (CMP), Contaminants, Biochemicals
Federal

This dataset contains the growth and survival data for Fathead minnow (Pimephales promelas) exposed to sediment from twelve sites within the Hamilton Harbour Area of Concern, as well as reference sediment (a mixture of sediment from two reference sites within Lake Erie, Long Point Marsh and Long Point Bay). The embryo-larval Fathead minnow exposure occurred over a three week period. Exposure was done from the egg stage (which lasted 5 days) to 9 and 16 days post hatch. Supplemental Information

Funding for this study was provided in part by the Government of Canada’s Great Lakes Action Plan (GLAP) and in support of Hamilton Harbour Area of Concern.

Last Updated: Jul. 23, 2021
Date Published: Mar. 18, 2019
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  Burlington, Hamilton Harbour, Long Point Bay, Long Point Marsh, Sediment exposure, Fathead Minnow (Pimephales promelas), Area of Concern (AOC), Great Lakes Action Plan (GLAP), Growth
Federal

This dataset contains the growth and survival data for Fathead minnow (Pimephales promelas) exposed to sediment from eleven sites within the St. Marys Area of Concern, as well as reference sediment (a mixture of sediment from two reference sites within Lake Erie, Long Point Marsh and Long Point Bay). The embryo-larval Fathead minnow exposure occurred over a three week period. Exposure was done from the egg stage (which lasted 5 days) to 9 and 16 days post hatch. Supplemental Information

Funding for this study was provided in part by the Government of Canada’s Great Lakes Action Plan (GLAP) and in support of St. Marys Area of Concern.

Last Updated: Jul. 29, 2021
Date Published: May 9, 2018
Organization: Environment and Climate Change Canada
Formats: CSV HTML
Keywords:  St. Marys River AOC, Burlington, Long Point Bay, Long Point Marsh, Great Lakes Action Plan (GLAP), Area of Concern (AOC), Sediment exposure, Growth, Survival
Date modified: