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These substances were identified for action under the Chemicals Management Plan (CMP). This screening assessment focuses on 6 of 7 substances referred to collectively as the Naphthalene Sulfonic Acids and Salts (NSAs) Group.

Venlafaxine is an antidepressant and anti-anxiety drug that has been detected in municipal wastewater at low micrograms per litre (ug/L) concentrations. In this study, the nest-defense behavior of adult male fathead minnows (Pimephales promelas) was observed in fish exposed for a full lifecycle to venlafaxine nominal concentrations. Nest-defense behaviors quantified were the time taken to contact a dummy intruder fish (on a flexible stick, held near each nest) and the number of contacts made during a 1 minute period. This study is the first to assess reproductive behaviors in fish exposed to an antidepressant over a full lifecycle.

Venlafaxine is an antidepressant and anti-anxiety drug that has been detected in municipal wastewater at low concentrations. To assess the potential of this compound to affect the survival, development and reproductive capacity of fish, we exposed Fathead minnow (Pimephales promelas) over a full lifecycle in a flow-through system to nominal venlafaxine concentrations. During the 167–168 day exposure, no significant changes were observed in survival, or the weights and lengths of Fathead minnows. At maturity, there were no significant differences relative to controls in condition factor, liver-somatic index, or secondary sex characteristics in the venlafaxine exposed male or female fish.

Substituted diphenylamine antioxidants (SDPAs) and benzotriazole UV stabilizers (BZT-UVs) are additives used in industrial and consumer products to prevent degradation or colour change of materials, but their environmental fate and disposition are not well characterized. In this study, SDPAs and BZT-UVs were analyzed in liquid and solid samples collected from wastewater treatment plants (WWTPs) in Canada to investigate the occurrence and fate of these contaminants. SDPAs and BZT-UVs were effectively removed from the liquid stream in most WWTPs mainly through sludge sorption and separation, but biotransformation, UV treatment and filtration may also contribute to removal of some contaminants in advanced treatment plants. In contrast, the removal efficiency of target contaminants using chemically assisted primary treatment was low, likely due to the short hydraulic retention time of this site.

Substituted phenylamine antioxidants (SPAs) are produced in relatively high volumes and used in a range of applications (e.g., rubber, polyurethane); however, little is known about their toxicity to aquatic biota. Therefore, current study examined the effects of chronic exposure (28 days) to four sediment-associated SPAs on epibenthic (Hyalella azteca) and endobenthic (Tubifex tubifex) organisms. In addition, acute (96-hour), water-only exposures were conducted with H. azteca. The data generated from this study will support effect characterization for ecological risk assessment.

Propranolol is a human pharmaceutical b-blocker that has been detected in municipal wastewater effluents in low concentrations. To assess the potential of this compound to affect fish, Fathead minnow (Pimephales promelas) were exposed for a life cycle in a flow-through system to nominal propranolol concentrations. During the 162-day to 165-day exposure, no significant changes in weights or lengths were seen in Fathead minnows, although the highest concentration of propranolol did cause a 15% decrease in survival of larval and juvenile stage fish compared with controls. At maturity, there were no significant changes in condition factor, liver-somatic index, or secondary sex characteristics in propranolol-exposed male or female fish.

Synthetic dyes are extensively used in many industrial and consumer products, including paper productions, leather tanning, food colouring, personal care products (examples being; hair colour, deodorant etc.). Synthetic dyes are also used in textile paints. No method has been able to completely remove these pollutants from wastewater and 10-15% of the dyes eventually enter aquatic ecosystem. In Canada as part of the Government of Canada's Chemicals Management Plan (CMP), substances that are used in industries or imported in as products are being assessed for potential human and environmental toxicity.

This study set out to provide an up-to-date portrait of the per- and polyfluoroalkyl substances (PFAS) contamination status in a freshwater food web from the St. Lawrence River (QC, Canada). Water, sediments, aquatic vegetation, invertebrates, and some fish species were targeted for analysis. All data are a part subject of a publication containing method details, full QA/QC, interpretation and conclusions: Munoz G, Mercier L, Duy SV, Liu J, Sauvé S, Houde M. Bioaccumulation and trophic magnification of emerging and legacy per- and polyfluoroalkyl substances (PFAS) in a St. Lawrence River food web. Environ Pollut.

Azo dyes are synthetic compounds used as industrial colorants, and some are predicted to be inherently toxic, bioaccumulative, and/or persistent based upon their chemical composition. This study addressed data gaps in current research which included the need to evaluate the toxicity of hydrophobic azo dyes to benthic invertebrates. The toxicity of a solvent dye, Sudan Red G (SRG), and two disperse dyes, Disperse Yellow 7 (DY7) and Disperse Orange 13 (DO13), to Hexagenia spp. and Tubifex tubifex was assessed in spiked-sediment exposures.

Substituted phenylamine antioxidants (SPAs) are used in the production of a variety of consumer products (lubricants, dyes, and polymers). Substituted phenylamine antioxidants (SPAs) increase the life of consumer products by preventing the chain reaction of free radical production initiated by exposure to heat, oxygen, ozone, radiation and stress. It is important to consider that based on their physicochemical properties, substituted phenylamine antioxidants (SPAs) are likely to partition into sediment when they enter an aquatic system. Thus the most likely environmentally relevant pathway for fish to become exposed to SPAs would be through contaminated sediment.