Grants and Contributions:
Agreement Number:
-
Agreement Value:
$150,000.00
Agreement Date:
Mar 16, 2020 -
Description:
UNDERSTANDING MICROGRAVITY-INDUCED BONE LOSS THROUGH IN VIVO SIMULATED MICROGRAVITY EXPERIMENTS
Following a space mission, astronauts experience severe bone thinning and increased risks of fracture when back on Earth. This anomaly is due to microgravity exposure. The aim of this study is to reproduce and expose fish larvae to a simulated microgravity on Earth, and to analyse the effects on the cells of the skeleton. Fish bones strongly resemble human bones in structure. They utilize similar cell types to secrete, mineralize and degrade bone matrix, and similar signaling pathways for cell-cell communication. Thus, fish are a good model to understand the causes underlying the microgravity-induced bone fragility observed in astronauts
Organization:
Canadian Space Agency
Location:
Halifax, Nova Scotia, CA
Reference Number:
003-2019-2020-Q4-04364
Agreement Type:
Grant
Report Type:
Grants and Contributions
Additional Information:
The amount allocated covers more than one fiscal year.
Late Disclosure:
Expected quarter 4 2020-2021
Disclosed quarter 3 2021-2022
Recipient's Legal Name:
Mount Saint Vincent University