Title:
Understanding Microgravity-Induced Bone Loss Through in Vivo Simulated Microgravity Experiments
Agreement Number:
19HLSRM01
Agreement Value:
$150,000.00
Agreement Date:
Mar 16, 2020 - Mar 31, 2022
Description:
UNDERSTANDING MICROGRAVITY-INDUCED BONE LOSS THROUGH IN VIVO SIMULATED MICROGRAVITY EXPERIMENTS
Following a space mission, astronauts experience severe bone thinning and increased risks of fracture when back on Earth. This anomaly is due to microgravity exposure. The aim of this study is to reproduce and expose fish larvae to a simulated microgravity on Earth, and to analyse the effects on the cells of the skeleton. Fish bones strongly resemble human bones in structure. They utilize similar cell types to secrete, mineralize and degrade bone matrix, and similar signaling pathways for cell-cell communication. Thus, fish are a good model to understand the causes underlying the microgravity-induced bone fragility observed in astronauts
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
Halifax, Nova Scotia, CA B3M 2J6
Reference Number:
003-2019-2020-Q4-04364
Report Type:
Grants and Contributions
Additional Information:
The amount allocated covers more than one fiscal year.
Late Disclosure:
Expected quarter 4 2020-2021
Disclosed quarter 3 2021-2022
Recipient's Legal Name:
Mount Saint Vincent University
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.