Title:
A cell-by-cell track structure and genomic examination of the DNA damage caused by low- and high-LET ionizing
Agreement Number:
19FAMCGB25
Agreement Value:
$99,990.00
Agreement Date:
Mar 25, 2020 - Mar 31, 2023
Description:
This research project aims to improve our understanding of the carcinogenic risk of cosmic radiation as encountered by astronauts in deep space. DNA mutations created by radiotherapy radiation on Earth will be studied. Findings will be useful not only for Canadian astronauts in deep space, but also for Canadian radiotherapy patients and radiation oncology physicians on Earth.
The proposed research approach examines the mutations caused by both sparsely and densely ionizing radiation in the DNA of human cells. It will consist in taking samples of cells, exposing them to both forms of radiation. A new technology in the form of single-cell DNA sequencing will be used to identify and compare the mutations created in each sample.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
Montreal, Quebec, CA H3H 2R9
Reference Number:
003-2020-2021-Q1-04459
Report Type:
Grants and Contributions
Recipient Type:
Not-for-profit organization or charity
Additional Information:
The amount allocated covers more than one fiscal year.
Late Disclosure
Recipient's Legal Name:
The Research Institute of the McGill University Health Center
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.