Title:
Simulated Microgravity in Understanding Knee Osteoarthritis
Agreement Value:
$277,805.00
Agreement Date:
Mar 17, 2022 - Mar 1, 2025
Description:
There is little attention on the potential impact of spaceflight associated low gravity (microgravity) on joint health. Osteoarthritis is the most common joint disease, and it primarily affects the mechanical loading bearing structures of the joint. Its negative effect on patients' quality of life is enormous. Over 10% of the Canadian population suffer from osteoarthritis, and the most common joint affected is the knee. Knee osteoarthritis is prevalent in females. The reason for the high incidence of knee osteoarthritis in females is not fully understood.
This project will explore the use of simulated microgravity to understand the basis of the prevalence of knee osteoarthritis in females. The findings of this project have the potential to discover novel drug targets for treating knee osteoarthritis to alleviate the burden of the disease in Canada and globally. Additionally, the project can potentially advance the use of simulated microgravity to study other joint disorders.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research
and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the
future.
Location:
Edmonton, Alberta, CA T6G 2E1
Reference Number:
003-2021-2022-Q4-00026
Report Type:
Grants and Contributions
Additional Information:
The amount allocated covers more than one fiscal year.
Recipient's Legal Name:
University of Alberta
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.