Title:
High Frame Rate Ultrasound Monitoring of Cerebral Blood Flow in Astronauts
Agreement Value:
$350,000.00
Agreement Date:
Mar 17, 2022 - Aug 31, 2026
Description:
Spaceflights pose risk on the cerebrovascular health of astronauts because humans are not accustomed to living under microgravity conditions. To facilitate cerebrovascular health assessments, it is essential to monitor cerebral blood flow accurately.
This project will seek to advance the state-of-art in monitoring cerebral blood flow in astronauts (and humans on Earth) by designing a new non-invasive diagnostic tool that can robustly measure the volume flow rate through the internal carotid artery that supplies circulation to the brain. These space physiology investigations and engineering innovations will be crucial for understanding the cerebrovascular health risks of human spaceflights, especially for long-term space missions to Mars that require multiple years of space travel.
Our research investigations will also directly benefit cerebrovascular health monitoring on Earth, particularly in facilitating early detection of cerebral hypoperfusion. As the elderly population is especially at risk of experiencing cerebral perfusion problems, the outcomes of this project will serve well to address diagnostic needs in promoting health aging of the elderly (and the overall Canadian population). In addition, the proposed technology will be relevant for use in remote, resource-limited communities in rural Canada. Moreover, from a talent development perspective, this project will foster several trainees to develop multidisciplinary expertise at the frontiers of space physiology and ultrasound technology. In turn, it will help Canada build an outstanding talent pool for medical device innovations.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research
and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the
future.
Location:
Waterloo, Ontario, CA N2L 3G1
Reference Number:
003-2021-2022-Q4-00048
Report Type:
Grants and Contributions
Additional Information:
The Proponent has requested to increase the grant amount by $50,000 to cover the National Research Council’s (NRC) fees for required Project flight hours due to a change in the NRC Flight Research Laboratory’s payment policy and to extend the Project completion date to August 31, 2026, in order to complete project activities.
Amendment Date
Oct 2, 2025
Recipient's Legal Name:
University of Waterloo
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.