Title:
Deciphering simulated microgravity and vibration effects on bone tissue in vivo
Agreement Number:
23HLSRM08
Agreement Value:
$150,000.00
Agreement Date:
Sep 29, 2023 - Jan 15, 2026
Description:
Following a space mission, astronauts experience severe bone thinning and increased risks of fracture when back on Earth. This bone anomaly is due to the exposure to an environment with reduced gravitational forces, namely microgravity. The aim of this study is to reproduce the microgravity environment on Earth using a ground-based instrument. Researchers will expose fish larvae to a simulated microgravity environment and analyse the effects on bone cells in the skeleton. The counter measure of vibration will also be examined separately and in combination with microgravity. The objectives of the study are to understand the cellular responses to these treatments in order to understand the microgravity induced bone loss observed in astronauts and to understand how to reduce these effects with vibration exposures. Fish bones strongly resemble human bones, in that the same cells are present, therefore these results will be relevant to humans.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
Halifax, Nova Scotia, CA B3M 2J6
Reference Number:
003-2023-2024-Q2-00007
Report Type:
Grants and Contributions
Amendment Date
Sep 20, 2025
Recipient's Legal Name:
Mount Saint Vincent University
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.