Title:
Exploring space health solutions through multiomic analysis of existing human spaceflight and analogue data
Agreement Number:
25HLSDM11
Agreement Value:
$75,000.00
Agreement Date:
Jul 31, 2025 - Jul 15, 2026
Description:
Spaceflight produces deleterious effects on multiple physiological systems (e.g., cardiovascular, cardiorespiratory, and postural controls) with astronauts in isolation and confinement (IC) in a microgravity environment. IC studies conducted on the ISS and the ground generally demonstrated altered neuro-immunomodulated responses, whose mechanisms may be related to chronic stress dysregulating the central nervous system (CNS). However, the effects of IC on CNS insult and multi-omic responses are yet to be investigated. The research team proposes to analyze datasets of previous flight experiments from NASA’s OSDR and Vivaldi 1 & 2 transcriptomic data from dry immersion analogue study. They aim to generate new knowledge and understanding of human spaceflight risks associated with CNS dysfunctions and contribute to evidence-based, prophylactic countermeasure development to mitigate the adverse risks associated with current spaceflight. Moreover, this research aims to translate this understanding to improve the health of Canadians on Earth who may be affected by related adverse effects.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
Burnaby, British Columbia, CA V5A 4W9
Reference Number:
003-2025-2026-Q2-00086
Report Type:
Grants and Contributions
Recipient's Legal Name:
Simon Fraser University
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.