Grants and Contributions:

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Title:

Molecularly Imprinted Opto-Fluidic Platform for Ultra-Sensitive Detection and Quantification of Biomarkers in Space

Agreement Number:

25FAYOB11

Agreement Value:

$288,090.00

Agreement Date:

Feb 20, 2026 - Mar 31, 2029

Description:

This project will develop a compact biosensing system, optimized and validated for space mission conditions, to deliver non-invasive, real-time, and high-fidelity health monitoring while providing students with hands-on experience in payload development, microfluidics, and optical sensing. The envisioned system integrates three state-of-the-art hardware innovations into a compact, reliable, and modular platform: an automated microfluidic unit for hands-free saliva collection, processing, and culture-free preconcentration in microgravity; a consumable Molecularly Imprinted Polymer (MIP) module for stable, selective biomarker capture; and an ultra-sensitive photothermal transducer for amplifying biomarker signals to detect ultra-low concentrations. The system’s software enables Internet-of-Things connectivity, enhanced with AI-driven predictive analytics, delivering results within minutes for intelligent, real-time health monitoring and decision support in space. The project will target three biomarkers relevant to proactive health management in space: cortisol, a stress hormone; IL-6, an inflammatory cytokine linked to immune dysregulation; and 8-OHdG, a marker of DNA oxidative damage associated with radiation exposure. Beyond astronaut health, the technology enables point-of-care diagnostics in remote and Arctic communities, strengthening healthcare resilience and reinforcing Canada’s leadership in space and terrestrial medical innovation.

Organization:

Canadian Space Agency

Expected Results:

The Research component of the program provides financial support to organizations to conduct space related research
and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.

Location:

Toronto, Ontario, CA M3J 1P3

Reference Number:

003-2025-2026-Q4-00036

Agreement Type:

Grant

Report Type:

Grants and Contributions

Recipient Type:

Academia

Additional Information:

The amount allocated covers more than one fiscal year.

Recipient's Legal Name:

York University

Program:

Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology

Program Purpose:

This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.

The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.