Title:
Manifestations of spaceflight-induced sub-clinical cardiovascular disease as a long-term health risk
Agreement Number:
19NASAHER2
Agreement Value:
$2,805,235.74
Agreement Date:
Aug 28, 2019 - Mar 31, 2031
Description:
Human spaceflight dramatically changes the daily exposures of the cardiovascular and musculo-skeletal systems to gravity
and physical loading. We will extend our previous observations of increased arterial stiffness and insulin resistance after 6-
month spaceflights to determine if 1-year in space exaggerates these conditions and promotes loss of calcium from bones
and uptake by arteries. Astronauts are extremely healthy on entry to space, but prolonged daily periods of physical
inactivity impair cardiometabolic and skeletal health. Our results should inform planning of physical countermeasures in
future long-duration explorations in space and convey the negative consequences of sedentary lifestyles in modern society.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
Waterloo, Ontario, CA N2J0E2
Reference Number:
003-2024-2025-Q3-00003
Agreement Type:
Contribution
Report Type:
Grants and Contributions
Recipient Type:
Not-for-profit organization or charity
Amendment Date
Jul 10, 2025
Recipient's Legal Name:
University of Waterloo
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.