Title:
A novel in vivo imaging approach to reveal the effects of space-mediated immune cell dysregulation in mouse models of cancer and inflammation
Agreement Number:
23FAWESB69
Agreement Value:
$247,918.00
Agreement Date:
Nov 1, 2024 - Sep 30, 2027
Description:
Astronauts face several health challenges while exposed to the harsh space environment. The immune system is one of the most severely affected systems. The main objectives of this study are to use Magnetic Particle Imaging (MPI) and Magnetic Resonance Imaging to investigate the effects of microgravity on Tumor-Associated Macrophages density within tumours, and to investigate the effects of microgravity on macrophage recruitment to sites of inflammation. The findings from this project will contribute to the understanding of how the immune system ages here on Earth.
Organization:
Canadian Space Agency
Expected Results:
The Research component of the program provides financial support to organizations to conduct space related research
and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Location:
London, Ontario, CA N6A 5B7
Reference Number:
003-2024-2025-Q3-00014
Report Type:
Grants and Contributions
Additional Information:
The amount allocated covers more than one fiscal year
Recipient's Legal Name:
University of Western Ontario
Program:
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Purpose:
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.
