Grants and Contributions:

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Title:

Improved treatment options for children with Dravet syndrome

Agreement Number:

925086

Agreement Value:

$25,000.00

Agreement Date:

Mar 15, 2019 - Mar 31, 2020

Description:

Dravet Syndrome (DS) is a treatment-resistant Early-onset Infantile Epileptic Encephalopathy, severely impairing development. Identification and characterization of underlying SCN1A mutations will dictate drug screening strategies, utilizing a CHEO-curated library of blood-brain-penetrant FDA-approved drugs. This bench-to-bedside collaboration (NRC/CHEO) will establish a translational pipeline towards personalized precision medicine for children with DS.

Organization:

National Research Council Canada

Expected Results:

In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators.

Location:

Ottawa, Ontario, CA K1H 8L1

Reference Number:

172-2018-2019-Q4-00045

Agreement Type:

Grant

Report Type:

Grants and Contributions

Recipient Business Number:

106914682

Recipient Type:

Not-for-profit organization or charity

Recipient's Operating Name:

Children's Hospital of Eastern Ontario Research Institute Inc.

Recipient's Legal Name:

Children's Hospital of Eastern Ontario Research Institute Inc.

Federal Riding Name:

Ottawa South

Federal Riding Number:

35077

Program:

Collaborative Science, Technology and Innovation Program – Ideation Fund

Program Purpose:

The Ideation Fund is intended to encourage, test and validate transformative research ideas generated by teams of NRC scientific personnel and external collaborators with complementary capabilities, acting as a demonstration phase for a continually-evolving suite of research and development (R&D) deliverables at the NRC. The fund supports exploratory research through two mechanisms: the New Beginnings Initiative and the Small Teams Initiative.

NAICS Code:

541710 - R&D in the physical, engineering and life sciences