Grants and Contributions:
Title:
A New High-Value Service: Establishment of Synthesis and Validation for Drug Discovery
Agreement Number:
916162
Agreement Value:
$193,000.00
Agreement Date:
Dec 1, 2018 - Mar 31, 2020
Description:
The proposed project will develop a new high-value service client; this involves establishing “synthesis and validation of hits” at 48Hour Discovery INC (48HD). The deliverable from achieving this objective is an extremely valuable investigational new drug (IND) enabling discovery pipeline. The pipeline consists of I) genetically-encoded library technology (BiGEL2) for the discovery of bicyclic ligands for cell-based targets, II) high throughput synthesis of selected discovered ligand, III) measurement of binding and specificity profile and IV) permeability assays. These scaffolds are stable and resilient to simulated gastrointestinal conditions and thus, the discovery platform will provide potentially oral and bioavailable therapeutics.
Organization:
National Research Council Canada
Expected Results:
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Location:
Edmonton, Alberta, CA T5K 0H2
Reference Number:
172-2018-2019-Q4-916162
Agreement Type:
Contribution
Report Type:
Grants and Contributions
Recipient Business Number:
719831695
Recipient Type:
For-profit organization
Additional Information:
This agreement has been amended 1 time(s). The end date of this agreements has been modified by 32 days.
Amendment Date
Dec 2, 2019
Recipient's Legal Name:
48Hour Discovery Inc.
Federal Riding Name:
Edmonton Centre
Federal Riding Number:
48014
Program:
Industrial Research Assistance Program – Contributions to Firms
Program Purpose:
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Coverage:
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation.
NAICS Code:
541710
Amendments: