Grants and Contributions:

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Title:

panKiller: Implementing a dual safety switch (suicide genes) in human pluripotent stem cells

Agreement Number:

947179

Agreement Value:

$400,000.00

Agreement Date:

Jan 1, 2020 - Jan 31, 2022

Description:

panKiller is an extension of panCELLa's proprietary FailSafe. panKiller is covered by the same patent as FailSafe: TOOLS AND METHODS FOR USING CELL DIVISION LOCI TO CONTROL PROLIFERATION OF CELLS. The patent was filed globally in most industrialized nations. panKiller involves the integration of a two-step safety switch. The first step utilizes FailSafe while the next step will utilize a second safety switch, panKiller, in order to eliminate all the therapeutic cells once therapy is complete and the therapeutic cells are no longer required. panKiller will link a suicide gene (iCaspase9) to a gene essential for cell survival (EEF2) in human induced pluripotent stem cells. There are currently no two-step safety switches on the market.

Organization:

National Research Council Canada

Expected Results:

The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization

Location:

Toronto, Ontario, CA M5G 0B7

Reference Number:

172-2019-2020-Q4-947179

Agreement Type:

Contribution

Report Type:

Grants and Contributions

Recipient Business Number:

808132328

Recipient Type:

For-profit organization

Recipient's Legal Name:

Pancella Inc.

Federal Riding Name:

University--Rosedale

Federal Riding Number:

35110

Program:

Industrial Research Assistance Program – Contributions to Firms

Program Purpose:

Coverage:

IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation.

NAICS Code:

3254