Grants and Contributions:
Title:
AI protein design for drugs and gene therapies
Agreement Number:
947523
Agreement Value:
$299,880.00
Agreement Date:
Mar 30, 2020 - Mar 29, 2024
Description:
Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Discovering these structures is important, since they determine a wide array of protein functions. However, experimental structure determination is costly and, as a result, atomic structures have only been determined for a tiny fraction of known proteins. The objective of this project is to develop an AI system capable of predicting protein-protein interaction and physicochemical properties of proteins solely from their amino acid sequences without any recourse to expensive, time-consuming and computationally prohibitive methods such as homology modelling, crystallography, nuclear magnetic resonance, molecular dynamics and macromolecular docking. The system, will allow for the design of proteins with specific properties by means of AI-based reverse engineering.
Organization:
National Research Council Canada
Expected Results:
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.
Location:
Ottawa, Ontario, CA K1N 6N5
Reference Number:
172-2019-2020-Q4-947523
Agreement Type:
Grant
Report Type:
Grants and Contributions
Recipient Business Number:
119278877
Recipient Type:
Academia
Additional Information:
This agreement has been amended 2 time. The end date of this agreements has been modified by 365 days
Amendment Date
Aug 31, 2022
Recipient's Legal Name:
University of Ottawa
Federal Riding Name:
Ottawa–Vanier
Federal Riding Number:
35078
Program:
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Program Purpose:
Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.
NAICS Code:
541710
Amendments: