Grants and Contributions:

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Title:

Developing of reagent combinations for the visual detection of SARS-CoV-2

Agreement Number:

955496

Agreement Value:

$100,000.00

Agreement Date:

Aug 14, 2020 - Nov 14, 2020

Description:

The team proposes to develop a molecular assay that identifies SARS-CoV-2 from saliva by a color change in 30 minutes. This assay consists of reagents that will amplify the SARS-CoV-2 genetic material 10 thousand fold. The amplified genetic material will bind to 13-nm gold nanoparticles coated with complementary single stranded DNA. The color of the solution changes because the gold nanoparticle will be assembled onto the SARS-CoV-2 amplified gene. The clustering of the gold nanoparticle changes how the electrons are moving, leading to different absorbance properties. This can be visualized by the change in the color of the solution of gold nanoparticles from red to blue. A positive detection is when the solution is blue. The team proposes to develop a formulation consisting of enzymes, salts, and gold nanoparticle-conjugates.

Organization:

National Research Council Canada

Expected Results:

In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.

Location:

Toronto, Ontario, CA M5G 1L5

Reference Number:

172-2020-2021-Q2-955496

Agreement Type:

Grant

Report Type:

Grants and Contributions

Recipient Business Number:

108162330

Recipient Type:

Academia

Recipient's Legal Name:

The Governing Council of the University of Toronto

Federal Riding Name:

University–Rosedale

Federal Riding Number:

35110

Program:

Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives

Program Purpose:

Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.

NAICS Code:

541710