Grants and Contributions:
Title:
Expanding the Biocatalytic Toolbox of Enzymes for the Sustainable Synthesis of Organic Compounds
Agreement Number:
969296
Agreement Value:
$25,000.00
Agreement Date:
Mar 24, 2021 - Sep 30, 2022
Description:
Modern drug development relies on the preparation of important “chiral” building blocks. One strategy to access such molecules in a green and sustainable manner is to exploit enzyme biocatalysts. However, such catalysts often evolved to preform chemical reactions on very specific structures. To overcome such limitations for chemical synthesis, directed evolution of enzymes will be explored. An important goal will be to evolve enzymes that can link molecules with photoactive motifs. The transformation of molecules using light is a green and sustainable technology. Through the development of novel enzymes, the preparation of high value molecules can be streamlined and made environmentally friendly through tandem biocatalytic and photocatalytic processes.
Organization:
National Research Council Canada
Expected Results:
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators.
Location:
Montreal, Quebec, CA H3T 1J4
Reference Number:
172-2020-2021-Q4-969296
Agreement Type:
Grant
Report Type:
Grants and Contributions
Recipient Business Number:
108160995
Recipient Type:
Academia
Recipient's Legal Name:
Université de Montréal
Federal Riding Name:
Outremont
Federal Riding Number:
24054
Program:
Collaborative Science, Technology and Innovation Program – Ideation Fund
Program Purpose:
The Ideation Fund is intended to encourage, test and validate transformative research ideas generated by teams of NRC scientific personnel and external collaborators with complementary capabilities, acting as a demonstration phase for a continually-evolving suite of research and development (R&D) deliverables at the NRC. The fund supports exploratory research through two mechanisms: the New Beginnings Initiative and the Small Teams Initiative.
NAICS Code:
541710 - R&D in the physical, engineering and life sciences