Title:
Molecular understanding for early diagnosis of the diseases of aging
Agreement Value:
$619,289.00
Agreement Date:
Feb 1, 2022 - Jan 31, 2026
Description:
The personal, societal, and economic burden of dementia is unsustainable. Diagnosis is currently established through cognitive and physical examination of patients already experiencing symptoms and therefore at advanced stages. The multidisciplinary team of this project will develop novel approaches to accurately diagnose risk of dementia in persons with preclinical (asymptomatic) Alzheimer’s Disease (AD) and Parkinson's Disease (PD)-related dementias. Through analysis of novel animal models as well as clinical lipidomics and metabolomics of blood and cerebrospinal fluid (CSF) profiles, the team seeks to provide a minimally invasive diagnosis of brain health. Better patient stratification, diagnosis at early, treatable disease stages as well as a better understanding of the biological changes underlying dementia risk will significantly reduce the need for long-term care and allow the aging population to enjoy longer independent and unassisted living.
Organization:
National Research Council Canada
Expected Results:
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.
Location:
Ottawa, Ontario, CA K1N 6N5
Reference Number:
172-2021-2022-Q4-987916
Report Type:
Grants and Contributions
Recipient Business Number:
119278877
Additional Information:
This agreement has been amended 1 time(s) the total amended value is $619,289.The end date of this agreement has been modified by 364 days.
Amendment Date
Jan 13, 2025
Recipient's Legal Name:
University of Ottawa
Federal Riding Name:
Ottawa--Vanier--Gloucester
Federal Riding Number:
35081
Program:
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Program Purpose:
Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.