Grants and Contributions:

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Title:

Linear Covalently Closed DNA Ministring (msDNA) Product and Production Process Development

Agreement Number:

1001542

Agreement Value:

$75,000.00

Agreement Date:

Feb 1, 2023 - Sep 30, 2023

Description:

This project will optimize the ministring DNA™ (msDNA™) production process to improve yield and purity while also making the process more stable, robust, and resistant to supply chain disruption, while also making the materials safer in the eyes of regulatory agencies by eliminating antibiotic usage from upstream production. Additionally, this project will evaluate next generation msDNA™ constructs to improve the therapeutic effectiveness of the drug substance. In summary, the outcomes of this project will improve the msDNA™ product, the production process, and facilitate the smooth and rapid transition to large-scale production to support Mediphage's genetic medicine program.

Organization:

National Research Council Canada

Expected Results:

The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization

Location:

Toronto, Ontario, CA M5G 0B7

Reference Number:

172-2022-2023-Q4-1001542

Agreement Type:

Contribution

Report Type:

Grants and Contributions

Recipient Business Number:

788308328

Recipient Type:

For-profit organization

Recipient's Legal Name:

Mediphage Bioceuticals, Inc.

Federal Riding Name:

University--Rosedale

Federal Riding Number:

35110

Program:

Industrial Research Assistance Program – Contributions to Firms

Program Purpose:

Coverage:

IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation.

NAICS Code:

54171