Grants and Contributions:
Title:
AI-Enabled Phenotypic Platform for Chemical Threat Assessment
Agreement Number:
1041349
Agreement Value:
$700,000.00
Agreement Date:
Feb 1, 2026 - Aug 2, 2027
Description:
Kapoose Creek Bio will adapt our existing AI-enabled phenotypic profiling platform for chemical threat assessment. Unlike chemistry-first detection that requires knowing what to look for, our activity-based approach identifies biological mechanism of action regardless of chemical novelty detecting even never-before-seen agents, such as novel derivatives that would evade traditional methods. The platform uses high-content cell imaging combined with Random Forest machine learning, leveraging a training set of 13,000+ bioactive compounds with known activity and mechanism. We will build a reference atlas of ~100 threat-relevant agents to further train mechanism classification. This capability will provide actionable intelligence within 48h.
Organization:
National Research Council Canada
Expected Results:
The expected results and outcomes of NRC Industrial Research Assistance Program is focused on growing small and medium-sized enterprises (SMEs) through innovation and wealth creation for Canada.
Location:
Vancouver, British Columbia, CA V6H 3Y4
Reference Number:
172-2025-2026-Q4-1041349
Agreement Type:
Contribution
Report Type:
Grants and Contributions
Recipient Business Number:
792582066
Recipient Type:
For-profit organization
Recipient's Legal Name:
Kapoose Creek Bio Corporation
Federal Riding Name:
Vancouver Centre
Federal Riding Number:
59034
Program:
Industrial Research Assistance Program
Program Purpose:
The purpose of Industrial Research Assistance Program Contributions to Firms is to provide support that assists small and medium-sized enterprises (SMEs) to advance their innovation knowledge and ability to innovate, grow through innovation and stimulate wealth creation for Canada.
Coverage:
Industrial Research Assistance Program projects stimulate wealth creation for Canada through technological innovation and strengthen Canadian innovation ecosystem by creating new industrial capacity.
NAICS Code:
541710