Grants and Contributions:

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Title:

COVID lipidomics and inflammation

Agreement Number:

967823

Agreement Value:

$297,381.00

Agreement Date:

Feb 26, 2021 - Feb 28, 2022

Description:

There is an urgent need for research focused on slowing and stopping the spread of SARS-CoV-2 in vulnerable populations. Canada’s elderly are particularly vulnerable to SARS-CoV-2 infection and in particular appear to be more susceptible to pulmonary and systemic hyper-inflammation, causing multiorgan failure following infection. Researchers hypothesize that lipids and metabolites act as major regulators of cytokines and inflammation response and thus provide an avenue for response-informed diagnostics and theragnostics. The research outlined in this Project will seek to understand how lipids and metabolites act as major regulators of cytokines and related inflammation response. Researchers aim to establish lipidomic and metabolomics indices of risk that may be used to identify, intervene, and mitigate the lasting negative effects of SARS-CoV-2 infection on the quality of life of survivors. This work aims to contribute to the overarching objectives of enhancing local, national, and international efforts to mitigate the related negative consequences of COVID-19.

Organization:

National Research Council Canada

Expected Results:

In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.

Location:

Ottawa, Ontario, CA K1N 6N5

Reference Number:

172-2020-2021-Q4-967823

Agreement Type:

Grant

Report Type:

Grants and Contributions

Recipient Business Number:

119278877

Recipient Type:

Academia

Recipient's Legal Name:

University of Ottawa

Federal Riding Name:

Ottawa–Vanier

Federal Riding Number:

35078

Program:

Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives

Program Purpose:

Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.

NAICS Code:

541710 - R&D in the physical, engineering and life sciences