Title:
CIIP Singapore - PEGASUS-BPE-CAR-T: Cost-Effective CAR-TCR Development with Pegasus Bio's BPE Plasmid Platform
Agreement Number:
1043376
Agreement Value:
$600,000.00
Agreement Date:
May 1, 2026 - Mar 31, 2028
Description:
CIIP Singapore -PEGASUS-BPE-CAR-T: Cell and gene therapy manufacturing faces major bottlenecks due to low-yield, high-cost, and difficult-to-scale plasmid DNA systems that limit efficient viral production. Pegasus Bio and CellVec are partnering to commercialize a high-performance plasmid DNA vector platform optimized for CAR-T and CAR-NK manufacturing. The project delivers a cost-effective, scalable, and regulatory-ready solution for gene delivery, improving expression, safety, and production efficiency. The PB BPE plasmid system will be offered to CGT developers through licensing and CDMO partnerships, with GMP processes transferred to qualified manufacturers. Joint IP will be protected through global patents, and a targeted market campaign will support commercialization.
Organization:
National Research Council Canada
Expected Results:
The Canadian International Innovation Program fosters and supports collaborative industrial research and development projects with high potential for commercialization between Canada and partner countries. It also stimulates bilateral science and technology networking and matchmaking activities to further new partnerships and accelerate the commercialization of research and development.
Location:
Charlottetown, Prince Edward Island, CA C1A 4P3
Reference Number:
172-2026-2027-Q1-1043376
Agreement Type:
Contribution
Report Type:
Grants and Contributions
Recipient Business Number:
760829879
Recipient Type:
For-profit organization
Recipient's Legal Name:
Pegasus Biotech Incorporated
Federal Riding Name:
Charlottetown
Federal Riding Number:
11002
Program:
Canadian International Innovation Program
Program Purpose:
The Canadian International Innovation Program fosters and supports collaborative industrial research and development projects with high potential for commercialization between Canada and partner countries. It also stimulates bilateral science and technology networking and matchmaking activities to further new partnerships and accelerate the commercialization of research and development.
Coverage:
The Canadian International Innovation Program supports industrial R & D partnerships and matchmaking activities between Canadian companies and foreign partners with a view to accelerating commercialization and facilitating market access.