Grants and Contributions:

Title:

Assessment of peptide and amino acid profiles following simulated dynamic gastrointestinal model digestion of collagen hydrolysate

Agreement Number:

EGP

Agreement Value:

$25,000.00

Agreement Date:

Aug 23, 2017 -

Organization:

Natural Sciences and Engineering Research Council of Canada

Location:

Quebec, CA

Reference Number:

GC-2017-Q2-00365

Agreement Type:

Grant

Report Type:

Grants and Contributions

Additional Information:

Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).

Recipient's Legal Name:

Kubow, Stan (McGill University)

Program:

Engage Grants for Universities

Program Purpose:

Genacol Canada Corporation Inc. manufactures a bovine-sourced hydrolyzed collagen supplement (Genacol®x000D
Original Formula), which has shown efficacy in two separate clinical trials for reducing joint pain. Followingx000D
digestion, hydrolyzed collagen yields bioavailable amino acids and peptides that can lead to the healthx000D
promoting properties of the supplement. There is presently no information, however, regarding the peptide andx000D
amino acid profiles generated from the digestion of the bovine-sourced Genacol collagen hydrolysate as thex000D
nature and profiles of these compounds will differ greatly depending upon of the type of processing used tox000D
produce the collagen hydrolysate and the food source of the collagen. In the present study, the profiles of thex000D
peptides and amino acids generated from digestive enzyme-mediated hydrolysis of the Genacol collagenx000D
product will be investigated using the dynamic simulated gut digestion model. This approach is the first step tox000D
ascertain the bioactive components contributing towards the health promoting properties of the Genacolx000D
collagen supplement and will aid in the development of more concentrated and potent hydrolyzed collagenx000D
products.