Grants and Contributions:

Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).

The long-term success of any implant is closely dependent on the interrelationship of various parameters,x000D
including biocompatibility of the bulk material, macroscopic and microscopic features of the implant surface,x000D
the status of the implant bed (host bone quality and quantity) and the surgical technique per se. In the case ofx000D
dental implants, the biological interactions take largely place at the interface between the bone tissue and thex000D
material. Consequently, the surface properties of implants play a crucial role in predicting their clinical success.x000D
In this context, the surface modification approach has recently gained an important and decisive place inx000D
biomaterials research, as tool to control the rate and quality of implant osseointegration. The current projectx000D
seeks to create well-defined topographies on the surface of conventional materials used in oral implantologyx000D
because there is growing evidence suggesting that bone cells perceive and respond to topographical cues.x000D
Therefore, our objective is to determine topographical features that facilitate early osseointegration and ensurex000D
long-term bone-implant anchorage.