Grants and Contributions:

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Title:

Manufacturing methods for mucoadhesive micelles

Agreement Number:

I2IPJ

Agreement Value:

$125,000.00

Agreement Date:

Sep 20, 2017 -

Organization:

Natural Sciences and Engineering Research Council of Canada

Location:

Ontario, CA

Reference Number:

GC-2017-Q2-04263

Agreement Type:

Grant

Report Type:

Grants and Contributions

Additional Information:

Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).

Recipient's Legal Name:

Sheardown, Heather (McMaster University)

Program:

Idea to Innovation

Program Purpose:

A novel mucoadhesive micelle has been developed which can be formulated with a therapeutic for drug delivery to the eye. Testing of micelles synthesized using RAFT polymerization containing cyclosporine A has demonstrated the efficacy of the formulation. Details can be found at: http://www.2020optimeyes.ca/Documents/I2I.pdf The proposed project will focus on creating the micelles using the more industrially-friendly and scalable free radical polymerization method, and exploring the potential manufacturing strategies of these drug loaded compounds. This will allow industrial partners to assess the licensing potential of these materials using a synthesis method consistent with their standard practices.