Grants and Contributions:
Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).
This Engage Grant will allow the Frampton Lab at Dalhousie University to assist Aspect Biosystems, thex000D
leading Canadian manufacturer of 3D bioprinters, with the development of novel bio-inks for the printing ofx000D
human skin equivalents. The Frampton lab will examine the growth characteristics of cultured humanx000D
keratinocytes (skin cells) in various bio-ink formulations that have potential to be used in the Aspectx000D
Biosystems 3D bioprinter. With the help of expert technicians from Aspect Biosystems, a set of the mostx000D
promising ink formulations will then be tested for compatibility with the microfluidic cartridges used in thex000D
Aspect Biosystems 3D bioprinter. The ink formulation that best balances cell growth properties with ease ofx000D
printing will then be utilized to demonstrate bioprinting of stratified epidermal tissues similar to skin.x000D
Processed tissue sections of these lab grown skin equivalents will be compared to sections of intact humanx000D
skin by histology.