Grants and Contributions:

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Title:
Development of fiber-optic, fluorescence lifetime-based imaging system for in vivo measures of signalling events
Agreement Number:
EGP
Agreement Value:
$25,000.00
Agreement Date:
Nov 8, 2017 -
Organization:
Natural Sciences and Engineering Research Council of Canada
Location:
Quebec, CA
Reference Number:
GC-2017-Q3-00578
Agreement Type:
Grant
Report Type:
Grants and Contributions
Additional Information:

Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).

Recipient's Legal Name:
Hébert, Terence (McGill University)
Program:
Engage Grants for universities
Program Purpose:

The ability to image and record cellular processes in living animals represents one of the most powerfulx000D
approaches in biological research. A variety of protein based optical indicators or "biosensors" have been usedx000D
to report cellular processes in cultured cells. However, imaging these biosensors in live animals hasx000D
traditionally been challenging, requiring costly transgenic animals and specialized microscopy equipment.x000D
These obstacles can be overcome with the recent development of affordable fiber-optic imaging systems,x000D
together with improved genetically-engineered biosensors and viral delivery methods. This Engage proposalx000D
aims to develop a novel fiber-optic photon counting system that would provide an affordable tool for recordingx000D
biosensor emissions in live animals.