Grants and Contributions:

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Title:

Improvement of new technology for assessment of adequate cerebral blood perfusion

Agreement Number:

EGP

Agreement Value:

$24,000.00

Agreement Date:

Mar 7, 2018 -

Organization:

Natural Sciences and Engineering Research Council of Canada

Location:

British Columbia, CA

Reference Number:

GC-2017-Q4-00028

Agreement Type:

Grant

Report Type:

Grants and Contributions

Additional Information:

Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019).

Recipient's Legal Name:

Ainslie, Philip (The University of British Columbia)

Program:

Engage Grants for universities

Program Purpose:

Cerebral autoregulation is a protective mechanism that maintains optimal brain blood flow and oxygen deliveryx000D
independent of changes in blood pressure. However, this protective mechanism has limits; blood pressures thatx000D
are too high or too low may exceed the ability of the brain's autoregulation mechanism(s) leading to anx000D
excessive level of under- or over- perfusion. For example, in surgical patients, blood pressure often exceeds thex000D
upper and/or lower limits of cerebral autoregulation, yet clinicians may not recognize that the patient's cerebralx000D
perfusion is compromised and thus do not intervene. This issue stems from an absence of evidence based,x000D
standardized and effective technology that can be used to evaluate cerebral autoregulation, especially inx000D
real-time. Therefore, improved cerebral autoregulation monitoring technology capable of detecting andx000D
informing clinicians about the patient's cerebral autoregulation and brain blood flow is necessary. The first stepx000D
to address this issue is the development of a standard for the improvement of cerebral autoregulationx000D
monitoring technology: the company (Medtronic) and University (Prof Ainslie) will be required to define andx000D
substantiate cerebral autoregulation monitoring approaches as part of a technology development process.