Grants and Contributions:

Back to search

Title:

Paper-based diagnostic device for colorectal cancer detection

Agreement Number:

CHRPJ

Agreement Value:

$402,900.00

Agreement Date:

Apr 25, 2017 -

Organization:

Natural Sciences and Engineering Research Council of Canada

Location:

Ontario, CA

Reference Number:

GC-2017-Q1-00238

Agreement Type:

Grant

Report Type:

Grants and Contributions

Additional Information:

Grant or Award spanning more than one fiscal year. (2017-2018 to 2020-2021)

Recipient's Legal Name:

Li, Yingfu (McMaster University)

Program:

Collaborative Health Research Projects

Program Purpose:

Colorectal cancer (CRC) affects over a million people globally, resulting in ~600,000 deathsx000D
annually. Early detection of CRC can significantly reduce the mortality of CRC. Whenx000D
neoplastic lesions are found while they are locally contained, the 5-year survival rate isx000D
greater than 90%; when they spread to nearby lymph nodes or distant organs, the rate dropsx000D
to 69% and 12%, respectively. The gold standard for CRC screening is colonoscopy; whilex000D
this procedure is effective, it is expensive and invasive, and can cause complications. Lessx000D
invasive or non-invasive methods are either prone to false-positives that requirex000D
follow-up with colonoscopy or very expensive to be used as a screening tool. In thisx000D
collaborative project, a team of academic researchers and clinicians will work together tox000D
develop a simple, litmus paper-like paper device for non-invasive detection of CRC. The testx000D
will be suited for routine CRC screening using stool samples. If successful, such a test willx000D
help save lives in Canada and around the world.